Tapentadol is partially metabolized through the hepatic enzymes CYP2C9, CYP2C19, and CYP2D6 so it innately has interactions with medication that greatly enhance or repress the action/expression of a number of of those enzymes, and with substrates of such enzymes (as a result of Competitiveness with the enzyme); some enzyme mediators/substrates https://miriamm110ksz8.shoutmyblog.com/profile